What exactly is Methyl Salicylate?

What exactly is Methyl Salicylate?

Therefore, What Exactly Is Methyl Salicylate? An in depth In Accordance With Menthol

Methyl salicylate is just a normal ester that executes really much like menthol. It really is commonly removed through vapor distillation of wintergreen leaves.

Based on WebMD, methyl salicylate can be found in many ointments that are topical purchased within the countertop for small joint aches or pains that are muscular. It can additionally be present in intimate items.

So, what exactly is methyl salicylate and exactly what does it do? Both methyl and menthol arno therapeutics salicylate are referred to as counterirritants, this means they cause cooling and sensations that are warming your skin. Counterirritants are mainly accountable for the title, and effect, known as “icy hot.”

These types of items shouldn’t be utilized on younger kids due to poisoning issues, which we’ll speak about later in this essay.

Wintergreen Oil

You might be wondering, what’s methyl salicylate? You shall usually hear about wintergreen“oil or oil of wintergreen.” Relating to an overview in the Journal of Alternative Complementary Medicine, methyl salicylate may be thepredominant ingredient when you look at the oil and it is the purest kind in the greatest concentration you certainly will find. Based on an oil wintergreen podcast through the Royal community of Chemistry, oil of wintergreen contains 96-99% methyl salicylate. Through the source that is same “…research has revealed that methyl salicylate is part of a plant’s toolbox within the battle against pathogens and herbivores.”

Methyl salicylate smells extremely highly of mint. Regardless of this, it will additionally be noted that this element will not belong within the mint genus of plant types. The burning sensation that is cold triggered through the TRPA1 channel. Methyl salicylate additionally activates the warmth channel TRPV1, which will be exactly the same channel regarded as activated by chile peppers like capsaicin. Often, wintergreen oil is employed along with peppermint oil, because the two in tandem are thought to attenuate effects that are beneficial. Wintergreen oil is acquired by vapor distillation regarding the warmed, water-macerated leaves. It’s often utilized interchangeably with sweet birch oil for flavoring meals and sweets.

Particular Products that Utilize Methyl Salicylate

Based on drugs.com and goodguide.com, you’ll find so many products which have methyl salicylate. Some items include…


Icy Hot Cream

Salonpas Pain Patch

Analgesic Balm



Menthocin Patch with Lidocaine

Soothee Patch




CVS Mouth Rinse Natural Citrus

CVS Antiseptic Mouth Rinse

K-Y Yours+Mine Partners Lubricant

Jason Natural Cosmetics Dandruff Relief Treatment Shampoo

Forever Residing Aloe Heat Cream

Colgate Peroxyl Antiseptic Oral Cleanser, Original

Orajel PM Toothache cream

CVS Intensive Strength Toothache relief

Young thieves that are living Ultra Toothpaste

Eco-Dent Specialcare Toothpowders Tartarguard

Comparing Methyl Salicylate to Aspirin

One research posted in the Annals of Pharmacotherapy aimed to analyze the effectiveness of methyl salicylate in platelet inhibition when compared with aspirin. Platelet aggregation is another real method of talking about platelets clumping together into the bloodstream. This can be regarding bloodstream clotting.

This research utilized a small test of nine healthier males when you look at the 30-46 age groups. All participants got 162 mg of aspirin before a washout period and then 5 g of 30% methyl salicylate preparation, both to be used on the anterior thighs. It absolutely was unearthed that “both aspirin and MS produced statistically significant platelet inhibition; aspirin decreased the AUC from 183; 139 to 292 to 85; 48 to 128 (p = 0.008) and MS decreased the AUC from 197; 118 to 445 to 112; 88 to 306 (p = 0.011).”

There is no difference that is large the two. This shows that methyl salicylate works because effectively as aspirin for platelet aggregation, at minimum in healthier individuals.

Poisoning Myths and Issues

Investigation for this substance on the web shall expose a few situation reports of baby death. two things should be noted about these. Such infant fatalities usually included the swallowing that is accidental of oil of wintergreen, the concentration that is highest of methyl salicylate you will get.

This does not imply that overdoses is only able to happen with ingestion; the substance may be consumed through your skin and then integrated into one’s system. But, it had been present in “Toxicity urban myths: the risk that is actual of Acrylic Use,” published into the Global Journal of Aromatherapy, that, “if 10?ml of the 2.5% formula of wintergreen oil had been to be reproduced all at a time to the skin and completely consumed, the dosage would represent exactly the same level of salicylate present in one single 325?mg aspirin tablet.”

For this reason oil of wintergreen is known as to be relatively low-risk with few effects that are side. Nonetheless, it is strongly suggested that brand new moms and dads avoid having the substance in the homely household, regarding the off-chance that a child could easily get their or her fingers onto it.

Additionally, it really is well worth noting that methyl salicylate happens to be limited for usage in cosmetic makeup products in Canada.

Trace Quantities Are Contained In Hemp Seed Oil

Among many health great things about hemp seed oil constituents, you may also find trace amounts of methyl salicylate. Hemp seed oil’s fatty acid content (omega-3s and omega-6s) is most remarkable as being a plus that is nutritional. The oil additionally contains 10-15% dietary fiber, 20-25% protein, and 20-30% carbs.

A bioassay posted in “The structure of Hemp Seed Oil and its particular prospectivebeing a essential way to obtain nutrition” reported from the methyl salicylate content of hemp seed oil. Additionally they reported on the other things contained in hemp seed oil, such as for example cannabidiol, ?-Sitosterol, tocopherols, and terpenes and terpenoids.

In Conclusion

So let’s review what we’ve learned hence far:

Methyl salicylate is really a normal ester that could be made organically or synthetically into the lab it is frequently removed via vapor distillation of wintergreen leaves.

Oil of wintergreen may be the strongest, purest concentration of methyl salicylate.

TRY NOT TO INGEST oil of wintergreen.

Methyl salicylate can also be present in over-the-counter items such as for example toothache ointments and muscle mass discomfort relievers to alleviate discomfort and produce a soothing feeling. Additionally it is sometimes found in lower amounts to flavor meals and sweets.

Wintergreen oil placed on your skin when you look at the right doses can express the same level of salicylate present in one single 325 mg aspirin tablet.

Methyl salicylate works efficiently against platelet aggregation—about as much as aspirin does.

Methyl salicylate can be found in hemp seed oil in trace quantities.

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